Semisoft clustering of single-cell data

DOI10.1073/PNAS.1817715116MaRDI QIDQ5222793zbMATH OpenOpenAlexWikidataFDO

Authors Lingxue Zhu, Jing Lei, Lambertus Klei, Kathryn Roeder, Bernie Devlin

Publication date 3 July 2019

Published in Proceedings of the National Academy of Sciences (Search for Journal in Brave)

Copyright license Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International

Full work available at URL https://doi.org/10.1073/pnas.1817715116

Mathematics Subject Classification ID

Classification and discrimination; cluster analysis (statistical aspects) (62H30) Applications of statistics to biology and medical sciences; meta analysis (62P10)

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(3)

• Model-based approach to the joint analysis of single-cell data on chromatin accessibility and gene expression
• A kernel non-negative matrix factorization framework for single cell clustering
• Regression‐based heterogeneity analysis to identify overlapping subgroup structure in high‐dimensional data

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