Simultaneous confidence intervals that are compatible with closed testing in adaptive designs

DOI10.1093/BIOMET/AST035MaRDI QIDQ2870262zbMATH OpenOpenAlexWikidataFDO

Authors Thomas Jaki, Martin Posch, Florian Klinglmueller, D. Magirr

Publication date 17 January 2014

Published in Biometrika (Search for Journal in Brave)

Copyright license Creative Commons Attribution 3.0 Unported

Full work available at URL https://doi.org/10.1093/biomet/ast035

zbMATH Keywords

closed testing principlecombination testsconditional errorsmultiple comparisonssimultaneous inference

Mathematics Subject Classification ID

Statistical decision theory (62C99) Parametric tolerance and confidence regions (62F25) Paired and multiple comparisons; multiple testing (62J15) Applications of statistics to biology and medical sciences; meta analysis (62P10)

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Cited in

(17)

• A comparison of methods for constructing confidence intervals after phase II/III clinical trials
• Simultaneous confidence regions for closed tests, including Holm-, Hochberg-, and Hommel-related procedures
• Test-compatible confidence intervals for adaptive two-stage single-arm designs with binary endpoint
• Informative simultaneous confidence intervals for the fallback procedure
• Simultaneous confidence regions corresponding to Holm's step-down procedure and other closed-testing procedures
• Point estimation for adaptive trial designs. II: Practical considerations and guidance
• Adaptive trial designs in diagnostic accuracy research
• Adaptive multiarm multistage clinical trials
• Optimizing subgroup selection in two-stage adaptive enrichment and umbrella designs
• Point estimation for adaptive trial designs. I: A methodological review
• Adjusting for treatment selection in phase II/III clinical trials with time to event data
• Estimation after subpopulation selection in adaptive seamless trials
• Flexible sequential designs for multi-arm clinical trials
• Designing multi-arm multi-stage clinical trials using a risk-benefit criterion for treatment selection
• Twenty-five years of confirmatory adaptive designs: opportunities and pitfalls
• Design and estimation in clinical trials with subpopulation selection
• Point and interval estimation in two-stage adaptive designs with time to event data and biomarker-driven subpopulation selection

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