Statistical composition of high-scoring segments from molecular sequences

DOI10.1214/AOS/1176347616MaRDI QIDQ922997zbMATH OpenOpenAlexFDO

Authors Samuel Karlin, Amir Dembo, Tsutomu Kawabata

Publication date 1990

Published in The Annals of Statistics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1214/aos/1176347616

zbMATH Keywords

DNAasymptotical extremal distribution of high aggregate segment scoresconditional Gaussian central limit lawsgeneral scoring schemei.i.d. letter valueslimiting letter composition of high-scoring segmentsmolecular sequences

Mathematics Subject Classification ID

Protein sequences, DNA sequences (92D20) Central limit and other weak theorems (60F05) Sums of independent random variables; random walks (60G50)

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• Problems of ruin and survival in economics: applications of limit theorems in probability
• Greedy lattice animals: Negative values and unconstrained maxima
• Scan statistics on Poisson random fields with applications in genomics
• Central limit theorems of partial sums for large segmental values
• Two parallel algorithms for finding all minimal maximum subsequences
• Statistical methods for DNA sequence segmentation
• Methods for assessing the statistical significance of molecular sequence features by using general scoring schemes.

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