Statistical methods in bioinformatics: an introduction
bioinformaticsDNA sequencesevolutionary modelsMarkov chainsphylogenetic tree estimationprotein sequencesstatistical inference
Introductory exposition (textbooks, tutorial papers, etc.) pertaining to statistics (62-01) Applications of statistics to biology and medical sciences; meta analysis (62P10) Introductory exposition (textbooks, tutorial papers, etc.) pertaining to biology (92-01) General biology and biomathematics (92B05) General biostatistics (92B15)
The aim of this book is to give an introductory account of some probability theory, statistics, and stochastic process theory appropriate to computational biology and bioinformatics. It enables to fill a gap in the literature concerning the statistical and probabilistic aspects of bioinformatics. The earlier chapters introduce the concepts of probability and statistics at an elementary level whereas the later chapters are immediately accessible to the trained statistician. The special attention is paid to material of interest in bioinformatics (e.g. extreme value theory, moment-generating functions, geometric random variables, information theory and entropy). So far as statistical theory is concerned, the focus is on discrete random variables, since (especially with DNA and protein sequences) these variables are more relevant to bioinformatics. Sufficient mathematical background consists of basic courses in calculus and linear algebra. The biological concepts that are used are explained or can be understood from the context.
- Statistical methods in bioinformatics. An introduction.
- Handbook of Statistical Bioinformatics
- Statistical methods in molecular biology.
- Statistical methods in biological and medical sciences
- Bioinformatics to biostochastics: statistical perspectives and tasks ahead
- scientific article; zbMATH DE number 3934278
- Statistical analysis of multivariate data in bioinformatics
- Statistical modelling and machine learning principles for bioinformatics techniques, tools, and applications
- Handbook of statistical bioinformatics.
- Power analysis of database search using multiple scoring matrices
- Bowker's test for symmetry and modifications within the algebraic framework
- On the tail probability of the longest well-matching run.
- An asymptotic maximum principle for essentially linear evolution models
- Statistical methods in bioinformatics. An introduction.
- Joint distributions associated with patterns, successes and failures in a sequence of multi-state trials
- Statistical modelling and machine learning principles for bioinformatics techniques, tools, and applications
- A survey of temporal data mining
- The reconstruction of an Hermitian Toeplitz matrix with prescribed eigenpairs
- The extremal behaviour over regenerative cycles for Markov additive processes with heavy tails
- On some stochastic models for replication of character strings
- Bioinformatics: organisms from Venus, technology from Jupiter, algorithms from Mars
- Bioinformatics. The machine learning approach.
- Statistical modeling and machine learning for molecular biology
- Cusum Test for Parameter Change Based on the Maximum Likelihood Estimator
- Introduction to Computational Genomics
- Statistical bioinformatics with R.
- Robust estimation for order of hidden Markov models based on density power divergences
- scientific article; zbMATH DE number 3934278 (Why is no real title available?)
- Statistical models in biology
- On the coverage of space by random sets
- scientific article; zbMATH DE number 2172892 (Why is no real title available?)
- Probabilistic modeling and analysis of DNA fragmentation
- Markov Bridges, Bisection and Variance Reduction
- Distributions of simple patterns in some kinds of exchangeable sequences
- scientific article; zbMATH DE number 6472286 (Why is no real title available?)
- Algebraic Statistics for Computational Biology
- Handbook of statistical bioinformatics.
- On waiting time distributions for patterns in a sequence of multistate trials
- Handbook of Statistical Bioinformatics
- On waiting time distributions associated with compound patterns in a sequence of multi-state trials
- Gibbs field approach for evolutionary analysis of regulatory signal of gene expression
- Spectral distortion measures for biological sequence comparisons and database searching
- Theory and mathematical methods in bioinformatics
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