An asymptotic maximum principle for essentially linear evolution models

DOI10.1007/S00285-004-0281-7MaRDI QIDQ1764646zbMATH OpenOpenAlexWikidataFDO

Authors Ellen Baake, Michael Baake, Anton Bovier, M. Klein

Publication date 25 February 2005

Published in Journal of Mathematical Biology (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/q-bio/0311020

zbMATH Keywords

ReversibilityAncestral distributionAsymptotics of leading eigenvalueLumpingMutation-selection models

Mathematics Subject Classification ID

Problems related to evolution (92D15) Eigenvalues, singular values, and eigenvectors (15A18) Applications of branching processes (60J85)

Abstract: Recent work on mutation-selection models has revealed that, under specific assumptions on the fitness function and the mutation rates, asymptotic estimates for the leading eigenvalue of the mutation-reproduction matrix may be obtained through a low-dimensional maximum principle in the limit N to infinity (where N is the number of types). In order to extend this variational principle to a larger class of models, we consider here a family of reversible N by N matrices and identify conditions under which the high-dimensional Rayleigh-Ritz variational problem may be reduced to a low-dimensional one that yields the leading eigenvalue up to an error term of order 1/N. For a large class of mutation-selection models, this implies estimates for the mean fitness, as well as a concentration result for the ancestral distribution of types.

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Cited in

(9)

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• Single-crossover dynamics: finite versus infinite populations
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