Interval estimation in a finite mixture model: Modeling \(P\)-values in multiple testing ap\-plications

DOI10.1016/J.CSDA.2005.11.011zbMath1157.62350OpenAlexW2016107327MaRDI QIDQ1010393

Jode Edwards, Gary L. Gadbury, Qinfang Xiang

Publication date: 6 April 2009

Published in: Computational Statistics and Data Analysis (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.csda.2005.11.011

zbMATH Keywords

bootstrapHessianMLEinterval estimationMCMCmicroarraygene expressionuniform beta mixture

Mathematics Subject Classification ID

Parametric tolerance and confidence regions (62F25) Point estimation (62F10)

Related Items (3)

A parametric model to estimate the proportion from true null using a distribution for \(p\)-values ⋮ A multivariate version of the Benjamini-Hochberg method ⋮ Latent class based multiple imputation approach for missing categorical data

Uses Software

• CODA
• BayesDA
• bootstrap
• Gibbsit

Cites Work

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• A mixture model approach for the analysis of microarray gene expression data.
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• Significance analysis of microarrays applied to the ionizing radiation response
• Selecting Differentially Expressed Genes from Microarray Experiments
• Simulation Run Length Control in the Presence of an Initial Transient
• Nonparametric analysis of replicated microarray experiments
• Randomization Tests for Small Samples: An Application for Genetic Expression Data
• Multiple-Testing Strategy for Analyzing cDNA Array Data on Gene Expression
• Assessing the accuracy of the maximum likelihood estimator: Observed versus expected Fisher information
• The Behavior of the P-Value When the Alternative Hypothesis is True
• Finite mixture models
• Importance of replication in microarray gene expression studies: Statistical methods and evidence from repetitive cDNA hybridizations
• Computational and Inferential Difficulties with Mixture Posterior Distributions
• A Direct Approach to False Discovery Rates
• Power and sample size estimation in high dimensional biology
• Large-Scale Simultaneous Hypothesis Testing

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