Improved inference of mutation rates. I: An integral representation for the Luria-Delbrück distribution

DOI10.1006/TPBI.2000.1496zbMath1011.92039OpenAlexW1981569971WikidataQ47214017 ScholiaQ47214017MaRDI QIDQ1597397

Thomas B. Kepler, Mihaela Oprea

Publication date: 9 June 2003

Published in: Theoretical Population Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1006/tpbi.2000.1496

zbMATH Keywords

integral representationmutation rateLuria-Delbrück distributionfinal cell numberinitial cell number

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Problems related to evolution (92D15) Cell biology (92C37)

Related Items (11)

Cellular replication limits in the Luria-Delbrück mutation model ⋮ Estimating change rates of genetic markers using serial samples: applications to the transposon IS6110 in Mycobacterium tuberculosis ⋮ Mean field mutation dynamics and the continuous Luria-Delbrück distribution ⋮ Sampling HIV intrahost genealogies based on a model of acute stage CTL response ⋮ The fixed-size Luria-Delbrück model with a nonzero death rate ⋮ The coalescence of intrahost HIV lineages under symmetric CTL attack ⋮ Accumulation of neutral mutations in growing cell colonies with competition ⋮ Convergence results for compound Poisson distributions and applications to the standard Luria–Delbrück distribution ⋮ A generalized Luria-Delbrück model ⋮ Scaling solution in the large population limit of the general asymmetric stochastic Luria-Delbrück evolution process ⋮ Improved inference of mutation rates. II: Generalization of the Luria-Delbrück distribution for realistic cell-cycle time distributions

Cites Work

• SOLUTION OF A PROCESS OF RANDOM GENETIC DRIFT WITH A CONTINUOUS MODEL
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