A hybrid cellular automaton model of clonal evolution in cancer: the emergence of the glycolytic phenotype

DOI10.1016/J.JTBI.2007.10.038zbMath1397.92327OpenAlexW2015594324WikidataQ33757776 ScholiaQ33757776MaRDI QIDQ1788573

Alexander R. A. Anderson, Philip Gerlee

Publication date: 8 October 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc2846650

zbMATH Keywords

mathematical modelcellular automatonevolutionary dynamicshybridglycolysisclonal evolutionmicro-environmentanaerobic metabolismresponse networktumourigenesis

Mathematics Subject Classification ID

PDEs in connection with biology, chemistry and other natural sciences (35Q92) Medical applications (general) (92C50) Developmental biology, pattern formation (92C15) Cellular automata (computational aspects) (68Q80) Cell biology (92C37)

Related Items (14)

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Uses Software

• JAMA

Cites Work

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• Unnamed Item
• Nonlinear simulation of tumor necrosis, neo-vascularization and tissue invasion via an adaptive finite-element/level-set method
• Evolving interfaces via gradients of geometry-dependent interior Poisson problems: application to tumor growth
• Continuous and discrete mathematical models of tumor-induced angiogenesis
• The role of cell-cell interactions in a two-phase model for avascular tumour growth
• Evolutionary game theory in an agent-based brain tumor model: exploring the `genotype-phenotype' link
• The role of acidity in solid tumour growth and invasion
• Mathematical modelling of dynamic adaptive tumour-induced angiogenesis: clinical implications and therapeutic targeting strategies
• Metabolic changes during carcinogenesis: potential impact on invasiveness
• A mathematical model of breast cancer development, local treatment and recurrence
• An evolutionary hybrid cellular automaton model of solid tumour growth
• Microenvironment driven invasion: a multiscale multimodel investigation
• Free boundary value problems associated with the growth and development of multicellular spheroids
• Mathematical Modelling of Tumour Invasion and Metastasis
• A hybrid mathematical model of solid tumour invasion: the importance of cell adhesion
• Simple ODE models of tumor growth and anti-angiogenic or radiation treatment

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