MAPK's networks and their capacity for multistationarity due to toric steady states

DOI10.1016/J.MBS.2014.12.010zbMath1315.92029arXiv1403.6702OpenAlexW2085115930WikidataQ50965750 ScholiaQ50965750MaRDI QIDQ2344608

Adrián G. Turjanski, Mercedes Pérez Millán

Publication date: 15 May 2015

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/1403.6702

zbMATH Keywords

mass-action kineticsmultistationaritysignaling networksMAPKtoric steady states

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Cell biology (92C37)

Related Items (6)

An all-encompassing global convergence result for processive multisite phosphorylation systems ⋮ Emergence of oscillations in a mixed-mechanism phosphorylation system ⋮ Regions of multistationarity in cascades of Goldbeter-Koshland loops ⋮ Identifying the parametric occurrence of multiple steady states for some biological networks ⋮ Detecting binomiality ⋮ A global convergence result for processive multisite phosphorylation systems

Uses Software

• Matlab
• SINGULAR

Cites Work

• Complex-linear invariants of biochemical networks
• An algebraic approach to signaling cascades with \(n\) layers
• Chemical reaction systems with toric steady states
• Multistationarity in mass action networks with applications to ERK activation
• Toric dynamical systems
• The rational parameterisation theorem for multisite post-translational modification systems
• Multistationarity in sequential distributed multisite phosphorylation networks
• Sign conditions for injectivity of generalized polynomial maps with applications to chemical reaction networks and real algebraic geometry

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