An empirical Bayes testing procedure for detecting variants in analysis of next generation sequencing data

DOI10.1214/13-AOAS660zbMath1283.62011arXiv1401.2278MaRDI QIDQ2441858

Zhigen Zhao, Zhi Wei, Wei Wang

Publication date: 28 March 2014

Published in: The Annals of Applied Statistics (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/1401.2278

zbMATH Keywords

optimalitymultiplicity controlBayesian FDRvariant call

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Biochemistry, molecular biology (92C40) Empirical decision procedures; empirical Bayes procedures (62C12)

Related Items

A simple yet efficient method of local false discovery rate estimation designed for genome-wide association data analysis, An empirical Bayes testing procedure for detecting variants in analysis of next generation sequencing data, An empirical Bayes change-point model for transcriptome time-course data, On simultaneous calibration of two-sample t-tests for high-dimension low-sample-size data, One-sided empirical Bayes test for location parameter in Gamma distribution, Two-sided empirical Bayes test for location parameter in the gamma distribution

Uses Software

• GATK
• Samtools
• vipR
• SNVer

Cites Work

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