A Treatment Allocation Procedure for Sequential Clinical Trials

DOI10.2307/2530497MaRDI QIDQ3865347zbMATH OpenOpenAlexWikidataFDO

Authors Colin B. Begg, Boris Igelwicz

Publication date 1980

Published in Biometrics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.2307/2530497

zbMATH Keywords

linear modelssequential clinical trialsstratificationtreatment allocation procedure

Mathematics Subject Classification ID

Empirical decision procedures; empirical Bayes procedures (62C12) Factorial statistical designs (62K15) Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cited in

(27)

• Some large trial properties of minimum likelihood allocation
• Robust allocation schemes for clinical trials with prognostic factors
• Optimal designs for dose-escalation trials and individual allocations in cohorts
• On the almost sure convergence of adaptive allocation procedures
• Predictability of designs which adjust for imbalances in prognostic factors
• Effect of design-adaptive allocation on inference for a regression parameter: Two-group, single-covariate and double-covariate cases
• A general scheme for sequential treatment allocation vith balancing for prognostic factors in clinical trials
• Balancing treatment allocation over continuous covariates: a new imbalance measure for mini\-mization
• A General Multi-Treatment Adaptive Design for Multivariate Responses
• Generalized Delayed Response in Randomized Play-the-Winner Rule
• SEQUENTIAL METHODS IN CLINICAL TRIALS*
• Algorithms for minimization randomization and the implementation with an R package
• Matching on-the-fly: sequential allocation with higher power and efficiency
• Adaptive designs for binary treatment responses in phase III clinical trials: controversies and progress
• Randomization, balance, and the validity and efficiency of design-adaptive allocation methods
• A New and Unified Family of Covariate Adaptive Randomization Procedures and Their Properties
• The Efficient Covariate-Adaptive Design for high-order balancing of quantitative and qualitative covariates
• Minimization in randomized clinical trials
• Regression-based multiple treatment effect estimation under covariate-adaptive randomization
• Adaptive randomization for balancing over covariates
• Sample size re-estimation for covariate-adaptive randomized clinical trials
• k-resolution sequential randomization procedure to improve covariates balance in a randomized experiment
• A better alternative to stratified permuted block design for subject randomization in clinical trials
• Asymptotic properties of covariate-adaptive randomization
• A simple, flexible, and effective covariate-adaptive treatment allocation procedure
• Statistical properties of minimal sufficient balance and minimization as methods for controlling baseline covariate imbalance at the design stage of sequential clinical trials
• Handling covariates in the design of clinical trials

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