A model for estimating environmental risk using multidimensional quantal response surfaces

DOI10.1016/0895-7177(93)90092-DMaRDI QIDQ1804082zbMATH OpenOpenAlexFDO

Authors Dovalee Dorsett, P. L. Odell

Publication date 29 June 1993

Published in Mathematical and Computer Modelling (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/0895-7177(93)90092-d

zbMATH Keywords

bioassay experimentscomputer simulationseffects of errorsestimating environmental riskfrequencies of concentrations of dosagesmultidimensional quantal response surfacesrobustnesssensitivitystimulitime series

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) General biostatistics (92B15)

Review text

The purpose of this paper is to formulate a model for estimating risk to a specified population by combining information gained in performing bioassay experiments in a laboratory with estimates of the frequencies of concentrations of dosages of several stimuli in the environment. The model formulated defines a mathematical foundation from which the usual spectrum of statistical estimators for risk can be directly developed, from which computer simulations can be designed and performed, and from which empirical hypotheses can be formulated. The model is based on simple probability concepts which are quite general; hence, the model has wider applicability than just environmental sciences.

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Cites work

• Cumulative Frequency Functions
• General models for quantal response to the joint action of a mixture of drugs
• scientific article; zbMATH DE number 3976122 (Why is no real title available?)
• scientific article; zbMATH DE number 3703820 (Why is no real title available?)
• scientific article; zbMATH DE number 3354430 (Why is no real title available?)
• scientific article; zbMATH DE number 3400223 (Why is no real title available?)
• scientific article; zbMATH DE number 3073468 (Why is no real title available?)
• Some Concepts of Dependence

Cited in

(11)

• A Lagrange-Gamma multihit dose-response model for risk assessment
• A multivariate approach to risk assessment of environmentally occurring chemicals
• Species non-exchangeability in probabilistic ecotoxicological risk assessment
• Uncertainty Modeling in Dose Response
• Environmental risk assessment model for low dose extrapolation^∗
• scientific article; zbMATH DE number 1525971 (Why is no real title available?)
• A note on tests for interaction in quantal response data
• A nonlinear threshold model for community response to environmental hazards
• An analytical treatment of potential hazard and risk assessment for environmental chemicals
• Is correlation dimension a reliable proxy for the number of dominant influencing variables for modeling risk of arsenic contamination in groundwater?
• A loss function approach to identifying environmental exceedances

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