A semiparametric sequential algorithm for estimation of dose-response curve

DOI10.1080/07474946.2013.774616MaRDI QIDQ4924128zbMATH OpenOpenAlexFDO

Authors Joseph D. Warfield, Anindya Roy

Publication date 30 May 2013

Published in Sequential Analysis (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1080/07474946.2013.774616

zbMATH Keywords

sequential designlink functionconstrained optimal designisotonic smoothing spline

Mathematics Subject Classification ID

Nonparametric regression and quantile regression (62G08) Applications of statistics to biology and medical sciences; meta analysis (62P10) Optimal statistical designs (62K05) Sequential statistical design (62L05)

Recommendations

• Sequential design for response curve estimation
• Efficient Sequential Designs With Binary Data
• Robustness of Design in Dose–Response Studies
• Sequential design for binary dose-response experiments
• Sequential Designs in Bioassay

Cites work

• scientific article; zbMATH DE number 47310 (Why is no real title available?)
• Bayesian optimal designs for phase I clinical trials
• Continual Reassessment Method: A Practical Design for Phase 1 Clinical Trials in Cancer
• Dose finding using the biased coin up-and-down design and isotonic regression
• Estimating Smooth Monotone Functions
• Estimating a smooth monotone regression function
• Generalized linear models. With applications in engineering and the sciences
• Isotonic smoothing splines under sequential designs
• Monotone nonparametric regression
• Nonparametric kernel regression subject to monotonicity constraints
• Optimal Bayesian design applied to logistic regression experiments
• Regression analysis under link violation
• Sequential Designs in Bioassay
• The Theory of Response‐Adaptive Randomization in Clinical Trials

Cited in

(8)

• On optimal designs for clinical trials: an updated review
• Semiparametric Dose Finding Methods
• A Semiparametric Response Surface Model for Assessing Drug Interaction
• On the efficiency of nonparametric variance estimation in sequential dose-finding
• Semiparametric Curve Alignment and Shift Density Estimation for Biological Data
• Adaptive clinical trial designs for phase I cancer studies
• Efficient Sequential Designs With Binary Data
• Dose-response curve estimation: a semiparametric mixture approach

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