An improved approximation for assessing the statistical significance of molecular sequence features

DOI10.1239/JAP/1053003554MaRDI QIDQ4435685zbMATH OpenFDO

Authors Sabine Mercier, Dominique Cellier, D. Charlot

Publication date 17 November 2003

Published in Journal of Applied Probability (Search for Journal in Brave)

Full work available at URL https://semanticscholar.org/paper/8c0fcb7b916e3105f863f1d40d0c02216d109391

zbMATH Keywords

applicationsasymptoticsexact distributionmaximumpartial sums

Mathematics Subject Classification ID

Sums of independent random variables; random walks (60G50)

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Cites work

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• Limit distribution of maximal non-aligned two-sequence segmental score
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• Methods for assessing the statistical significance of molecular sequence features by using general scoring schemes.
• Statistical composition of high-scoring segments from molecular sequences
• Strong limit theorems of empirical functionals for large exceedances of partial sums of i.i.d. variables
• The Erdős-Rényi law in distribution, for coin tossing and sequence matching
• Two moments suffice for Poisson approximations: The Chen-Stein method

Cited in

(5)

• Duality between the local score of one sequence and constrained hidden Markov model
• Applying statistical criteria to choose optimal metaparameters in gene fragment recognition
• Rapid and accurate estimates of statistical significance for sequence data base searches.
• scientific article; zbMATH DE number 1870225 (Why is no real title available?)
• Improvements on the distribution of maximal segmental scores in a Markovian sequence

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