Calculating the Statistical Significance of Changes in Pathway Activity From Gene Expression Data

DOI10.2202/1544-6115.1055MaRDI QIDQ5700455zbMATH OpenOpenAlexWikidataFDO

Authors Jörg Rahnenführer, Francisco S. Domingues, Jochen Maydt, Thomas Lengauer

Publication date 28 October 2005

Published in Statistical Applications in Genetics and Molecular Biology (Search for Journal in Brave)

Full work available at URL http://www.bepress.com/sagmb/vol3/iss1/art16/

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Biochemistry, molecular biology (92C40) Genetics and epigenetics (92D10)

Recommendations

• Bayesian gene set analysis for identifying significant biological pathways
• On testing the significance of sets of genes
• A statistical method for measuring activation of gene regulatory networks
• Covariance-based analyses of biological pathways
• Contextual analysis of gene expression data.

Cited in

(3)

• A statistical method for measuring activation of gene regulatory networks
• A hidden spatial-temporal Markov random field model for network-based analysis of time course gene expression data
• ModeScore: a method to infer changed activity of metabolic function from transcript profiles

Describes a project that uses

Uses Software

• GOstat
• FatiGO
• KEGG

This page was built for publication: Calculating the Statistical Significance of Changes in Pathway Activity From Gene Expression Data

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q5700455)