Denoising array-based comparative genomic hybridization data using wavelets

DOI10.1093/BIOSTATISTICS/KXI004MaRDI QIDQ5694481zbMATH OpenOpenAlexWikidataFDO

Authors

Publication date 4 October 2005

Published in Biostatistics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1093/biostatistics/kxi004

zbMATH Keywords

Array-CGHBreast tumor dataDenoisingHidden Markov modelsThresholdWavelet analysis

Mathematics Subject Classification ID

Nontrigonometric harmonic analysis involving wavelets and other special systems (42C40) Nonparametric inference (62G99) Applications of statistics to biology and medical sciences; meta analysis (62P10) Biochemistry, molecular biology (92C40)

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(13)

• Multiple testing of local extrema for detection of change points
• Fast estimation of posterior probabilities in change-point analysis through a constrained hidden Markov model
• A heuristic, iterative algorithm for change-point detection in abrupt change models
• Comparison of numerical representations of genomic sequences: choosing the best mapping for wavelet analysis
• Data denoising and post-denoising corrections in single cell RNA sequencing
• Function-on-function regression for the identification of epigenetic regions exhibiting windows of susceptibility to environmental exposures
• Hidden Markov models for the assessment of chromosomal alterations using high-throughput SNP arrays
• FDR control of detected regions by multiscale matched filtering
• Detecting genomic aberrations using products in a multiscale analysis
• Comparing segmentation methods for genome annotation based on RNA-seq data
• A Bayesian approach for locating change points in a compound Poisson process with application to detecting DNA copy number variations
• Approximation algorithms for speeding up dynamic programming and denoising acgh data
• A Modified Bayes Information Criterion with Applications to the Analysis of Comparative Genomic Hybridization Data

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