Detecting MicroRNA Targets by Linking Sequence, MicroRNA and Gene Expression Data

DOI10.1007/11732990_11MaRDI QIDQ3596284zbMATH OpenOpenAlexFDO

Authors Jim Huang, Quaid D. Morris, Brendan J. Frey

Publication date 30 August 2007

Published in Lecture Notes in Computer Science (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/11732990_11

zbMATH Keywords

gene expression datalinking sequencemicroRNApost-transcriptional degradation

Mathematics Subject Classification ID

Genetics and epigenetics (92D10)

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• Identification of specific sequence motifs in the upstream region of 242 human miRNA genes
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• RRSM with a data-dependent threshold for miRNA target prediction
• Detecting composite functional module in miRNA regulation and mRNA interaction network
• Identifying microRNA and gene expression networks using graph communities
• From mobility to crosstalk. A model of intracellular miRNAs motion may explain the RNAs interaction mechanism on the basis of target subcellular localization
• Activity of microRNAs and transcription factors in gene regulatory networks.
• A novel Bayesian multiple testing approach to deregulated miRNA discovery harnessing positional clustering
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• Research in Computational Molecular Biology
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• Genome-wide computational analyses of microRNAs and their targets from \textit{Canis familiaris}

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