A multiple time interval finite state projection algorithm for the solution to the chemical master equation (Q2456722)

This paper is concentrated to one computational difficulty that arises when system trajectories slowly drift over regions of the configuration space during long time intervals. A new approach for choosing and expanding the projection for the original finite state projection algorithm is presented. The authors introduce an approach to automatically choosing and expanding the projection necessary to achieve a desired accuracy and then illustrate this algorithm on a simplified model from the field of systems biology.