PrEP intervention in the mitigation of HIV/AIDS epidemics in China via a data-validated age-structured model (Q6044233)
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scientific article; zbMATH DE number 7686712
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | PrEP intervention in the mitigation of HIV/AIDS epidemics in China via a data-validated age-structured model |
scientific article; zbMATH DE number 7686712 |
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PrEP intervention in the mitigation of HIV/AIDS epidemics in China via a data-validated age-structured model (English)
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17 May 2023
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This paper studies PrEP intervention in the mitigation of HIV/AIDS epidemics in China via a data-validated age-structured model. The paper formulates the age-structured HIV/AIDS model with PrEP intervention for the transmission dynamics of HIV/AIDS. The existence of the positive solution for a non-dimensional form of the model is proved. The basic reproduction number is derived and the stability of the disease-free state is proved. The existence and stability of the endemic steady state of the system are obtained. Moreover, the paper establishes the demographic model corresponding to the age-structured model. Some numerical simulations have also been performed to validate the theoretical results.
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HIV/AIDS epidemics
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antiretroviral-based pre-exposure prophylaxis (PrEP)
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age structure
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antiretroviral therapy
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Markov chain Monte Carlo (MCMC)
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