Mathematical aspects of pattern formation in biological systems
Reaction-diffusion equations (35K57) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Research exposition (monographs, survey articles) pertaining to biology (92-02) General biology and biomathematics (92B05) Developmental biology, pattern formation (92C15) Genetics and epigenetics (92D10) Population dynamics (general) (92D25)
Mathematical modeling is quite a burgeoning field of study. Representing a natural phenomenon is challenging, a non-ending process that does evolve as we expand interdisciplinary studies. This book deals with the mathematical analysis of patterns encountered in biological systems, using a variety of functional analysis methods to prove the existence of solutions. It is the authors' own account and expansion of their results over a fifteen year period, which contributes to initiating a systematic program of rigorous mathematical investigation into pattern formation for large-scale amplitude patterns far from equilibrium in biologically relevant models. By reviewing the bifurcation of patterned states from unstable homogeneous steady states which differ from the standard instability approach by Turing, one can investigate large-amplitude patterns in the case of multiple spikes which concentrate at certain points of the underlying domain. Previous studies have introduced non-local eigenvalue problems in one-dimensional settings, this books extends that concept to general partial differential equations without any symmetry assumptions, but with only a smoothness requirement at the boundary. The book is not for lay readers but is ``\dots of interest to graduate students and researchers who are ACTIVE \dots. It is indeed written for advanced graduates and experts interested in the mathematics of pattern formation and reaction-diffusion equations. The linkage of results in the book to biological applications as well as highlighting their relevance to natural phenomena have nothing obvious for a beginner in this field. Also, little background information is provided at the beginning of most chapters. The mathematical proofs are quite robust and readers interested in the study of pattern formation will find it quite interesting to have a compilation of such an amount of information in one place. I would recommend other textbooks to someone interested or active in mathematical biology. However, this is a good reference source for various advanced theories and mathematical applications in this field. The book layout is excellent, but its greatest interest is the specific context in which it is written; to provide the reader with advanced theories on {\parindent= 0.5 cm \begin{itemize} \item[--] examining existence of spiky steady states in reaction-diffusion systems \item[--] exploring spatially homogeneous two-component activator-inhibitor system in 1 or 2-D, and finally \item[--] extending the theories by adding extra effects with specific roles in developmental biology such as spatial inhomogeneity, large reaction rates, convection, modified or altered boundary conditions and saturation terms (to name a few). \end{itemize}}
- A mathematical model for pattern formation in biological systems
- Reaction-diffusion models for biological pattern formation
- scientific article; zbMATH DE number 1116725
- scientific article; zbMATH DE number 51162
- On the role of basic production terms in an activator-inhibitor system modeling biological pattern formation
- Mathematical biology. Vol. 2: Spatial models and biomedical applications.
- Analysis on a generalized Sel'kov-Schnakenberg reaction-diffusion system
- On De Giorgi's conjecture: recent progress and open problems
- Stable boundary spike clusters for the two-dimensional Gierer-Meinhardt system
- The stability and slow dynamics of spot patterns in the 2D Brusselator model: the effect of open systems and heterogeneities
- Stable spike clusters for the precursor Gierer-Meinhardt system in \(\mathbb {R}^2\)
- Existence and stability of one-peak symmetric stationary solutions for the Schnakenberg model with heterogeneity
- Multi-bump ground states of the fractional Gierer-Meinhardt system on the real line
- Multi-spike patterns in the Gierer-Meinhardt system with a nonzero activator boundary flux
- Existence and stability of patterns in a reaction-diffusion-ODE system with hysteresis in non-uniform media
- Existence of multi-peak solutions to the Schnakenberg model with heterogeneity on metric graphs
- Unbounded mass radial solutions for the Keller-Segel equation in the disk
- Solutions of the Yamabe equation by Lyapunov-Schmidt reduction
- Stability analysis of spike solutions to the Schnakenberg model with heterogeneity on metric graphs
- Boundary layer solutions in the Gierer-Meinhardt system with inhomogeneous boundary conditions
- The existence and stability of spikes in the one-dimensional Keller-Segel model with logistic growth
- The existence of localized vegetation patterns in a systematically reduced model for dryland vegetation
- The stochastic Gierer-Meinhardt system
- Bifurcation and Turing patterns of reaction-diffusion activator-inhibitor model
- Discontinuous stationary solutions to certain reaction-diffusion systems
- Stability of multi-peak symmetric stationary solutions for the Schnakenberg model with periodic heterogeneity
- Concentration phenomena on \(Y\)-shaped metric graph for the Gierer-Meinhardt model with heterogeneity
- Pattern formation of a biomass-water reaction-diffusion model
- Stable spike clusters on a compact two-dimensional Riemannian manifold
- Stable and unstable periodic spiky solutions for the Gray-Scott system and the Schnakenberg system
- Bifurcation to coherent structures in nonlocally coupled systems
- A numerical framework for singular limits of a class of reaction diffusion problems
- Nonlocal eigenvalue problems arising in a generalized phase-field-type system
- Another mechanism to control invasive species and population explosion: ``ecological damping continued
- Extending the mathematical palette for developmental pattern formation: piebaldism
- Algorithms and complexity in biological pattern formation problems
- Influence of curvature, growth, and anisotropy on the evolution of Turing patterns on growing manifolds
- The effect of heterogeneity on one-peak stationary solutions to the Schnakenberg model
- Multi-peak solutions for the Schnakenberg model with heterogeneity on star shaped graphs
- Reaction-diffusion systems: experiments and theoretical models in biology and chemistry. Proceedings of a symposium held at the Research Institute for Mathematical Sciences, Kyoto University, Kyoto, Japan, April 25--27, 2000
- scientific article; zbMATH DE number 1705236 (Why is no real title available?)
- Explicitly solvable nonlocal eigenvalue problems and the stability of localized stripes in reaction-diffusion systems
- Existence and stability of a spike in the central component for a consumer chain model
- Mathematical study of pattern formation accompanied by heterocyst differentiation in multicellular cyanobacterium
- Spots, traps, and patches: asymptotic analysis of localized solutions to some linear and nonlinear diffusive systems
- Global existence and finite time blow-up of solutions of a Gierer-Meinhardt system
- On the Stability of Solutions of Semilinear Elliptic Equations with Robin Boundary Conditions on Riemannian Manifolds
- scientific article; zbMATH DE number 637043 (Why is no real title available?)
- Dynamical spike solutions in a nonlocal model of pattern formation
- Anomalous scaling of Hopf bifurcation thresholds for the stability of localized spot patterns for reaction-diffusion systems in two dimensions
- Pattern formation in a reaction-diffusion system with space-dependent feed rate
- Explicitly solvable eigenvalue problem and bifurcation delay in sub-diffusive Gierer-Meinhardt model
- Stable spike clusters for the one-dimensional Gierer-Meinhardt system
- On the Helmholtz equation and Dancer's-type entire solutions for nonlinear elliptic equations
- Symmetry methods in mathematical biology
- Weakly nonlinear analysis of peanut-shaped deformations for localized spots of singularly perturbed reaction-diffusion systems
- An asymptotic analysis of localized three-dimensional spot patterns for the Gierer-Meinhardt model: existence, linear stability, and slow dynamics
- Sufficient Turing instability conditions for the Schnakenberg system
- Hopf bifurcation from spike solutions for the weak coupling Gierer–Meinhardt system
- Hopf bifurcation analysis in a Gierer-Meinhardt activator-inhibitor model
- Existence and stability of symmetric and asymmetric patterns for the half-Laplacian Gierer-Meinhardt system in one-dimensional domain
- Competition instabilities of spike patterns for the 1D Gierer-Meinhardt and Schnakenberg models are subcritical
- Refined stability thresholds for localized spot patterns for the Brusselator model in \(\mathbb{R}^2\)
- Patterns in a fresh water tussock sedge model with two limit cycles
- Existence, nonexistence and uniqueness of positive stationary solutions of a singular Gierer-Meinhardt system
- Spatially periodic multipulse patterns in a generalized Klausmeier-Gray-Scott model
- Moving and jumping spot in a two-dimensional reaction-diffusion model
- The linear stability of symmetric spike patterns for a bulk-membrane coupled Gierer-Meinhardt model
- scientific article; zbMATH DE number 5262959 (Why is no real title available?)
- Existence of solutions to a new model of biological pattern formation
- Spike dynamics in the presence of noise
- Stability of Spike Solutions to the Fractional Gierer-Meinhardt System in a One-Dimensional Domain
- Preface: Special issues on nonlocal modeling, analysis, and computation
- New synchronized solutions for linearly coupled Schrödinger systems
- Large amplitude radially symmetric spots and gaps in a dryland ecosystem model
- Cluster solutions for the Fitzhugh-Nagumo system with Neumann boundary conditions
- Multiple mixed interior and boundary peaks synchronized solutions for linearly coupled Schrödinger systems
- Spiky patterns for the Schnakenberg model with advection term on Y-shaped metric graph
- Multi-spike solutions to the one-dimensional subcritical fractional Schnakenberg system
- Existence and Stability of Localized Patterns in the Population Models with Large Advection and Strong Allee Effect
- Spike solutions to the supercritical fractional Gierer-Meinhardt system
- Multi-spike patterns for the Gierer-Meinhardt model with heterogeneity on \(Y\)-shaped metric graph
- Analysis of the Hopf bifurcation in a diffusive Gierer-Meinhardt model
- Infinitely many solutions for nonlinear elliptic equations with oscillatory potentials
- Existence and stability of a boundary layer with an interior spike in the singularly perturbed shadow Gierer-Meinhardt system
- Multiplicity of 2-nodal solutions of the Yamabe equation
- Analysis of local bifurcations in a two-component reaction-diffusion system of activator-substrate type with no-flux boundary conditions
- From nonlinear Schrödinger equation to interacting particle system
- On the effects of advection and network structure in spiky patterns for the Gierer-Meinhardt model
- Infinitely many solutions for linearly coupled Schrödinger systems in \(\mathbb{R}^3\)
- From nonlinear Schrödinger equation to interacting particle system: \(1 < p < 2\)
- Delay-induced Hopf and Turing instabilities in a modified Brusselator reaction-diffusion model
- Modeling cholera transmission dynamics with antibiotic resistance and mutation: a PDE perspective
- The dynamics of the stochastic shadow Gierer-Meinhardt system
- A mathematical model for pattern formation in biological systems
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