Moment estimation in discrete shifting level model applied to fast array-CGH segmentation

DOI10.1111/STAN.12005MaRDI QIDQ6552759zbMATH OpenFDO

Authors Alberto Gandolfi, Matteo Benelli, Alberto Magi, S. Chiti

Publication date 10 June 2024

Published in Statistica Neerlandica (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1111/STAN.12005

zbMATH Keywords

array-CGHconfidence intervalsDNAfinite state spacemicroarraymoment estimatorsegmentationshifting level process

Mathematics Subject Classification ID

Markov chains (discrete-time Markov processes on discrete state spaces) (60J10) Point estimation (62F10) Parametric tolerance and confidence regions (62F25) Applications of statistics to biology and medical sciences; meta analysis (62P10) Genetics and epigenetics (92D10)

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Cites work

• A shifting level model algorithm that identifies aberrations in array-CGH data
• A very fast and accurate method for calling aberrations in array-CGH data
• Circular binary segmentation for the analysis of array-based DNA copy number data
• Estimating the Current Mean of a Normal Distribution which is Subjected to Changes in Time
• Hidden Markov models approach to the analysis of array CGH data
• Limit theorems for the shifting level process

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