Multiobjective approach to optimal control for a tuberculosis model
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Abstract: Mathematical modelling can help to explain the nature and dynamics of infection transmissions, as well as support a policy for implementing those strategies that are most likely to bring public health and economic benefits. The paper addresses the application of optimal control strategies in a tuberculosis model. The model consists of a system of ordinary differential equations, which considers reinfection and post-exposure interventions. We propose a multiobjective optimization approach to find optimal control strategies for the minimization of active infectious and persistent latent individuals, as well as the cost associated to the implementation of the control strategies. Optimal control strategies are investigated for different values of the model parameters. The obtained numerical results cover a whole range of the optimal control strategies, providing valuable information about the tuberculosis dynamics and showing the usefulness of the proposed approach.
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Cited in
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- Optimal control applied to vaccination and treatment strategies for various epidemiological models
- Multiobjective optimization to a TB-HIV/AIDS coinfection optimal control problem
- Optimal control using state-dependent Riccati equation of lost of sight in a tuberculosis model
- Optimal control in two strain pneumonia transmission dynamics
- Literature review: the vaccine supply chain
- An efficient numerical simulation and mathematical modeling for the prevention of tuberculosis
- Numerical study for time delay multistrain tuberculosis model of fractional order
- A multiobjective optimal control problem for the dynamics of an infectious disease with limited healthcare facilities and vaccination
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- A trust-region interior-point technique to solve multi-objective optimization problems and its application to a tuberculosis optimal control problem
- Modelling the transmission dynamics and optimal control strategies for HIV infection in China
- Uniform asymptotic stability of a fractional tuberculosis model
- An epidemic model for cholera with optimal control treatment
- Modeling and optimal control of HIV/AIDS prevention through PrEP
- The Burden of the Coinfection of HIV and TB in the Presence of Multi-drug Resistant Strains
- Optimal treatment strategies for musculoskeletal diseases
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