Support points of locally optimal designs for nonlinear models with two parameters

DOI10.1214/07-AOS560zbMATH Open1155.62053OpenAlexW3098355515MaRDI QIDQ1002170FDOQ1002170

Authors Min Yang, John Stufken 

Publication date 25 February 2009

Published in The Annals of Statistics (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/0903.0728

zbMATH Keywords

count dataPoisson modelbinary responseLoewner orderMichaelis-Menten modelmulti-stage experiment

Mathematics Subject Classification ID

Generalized linear models (logistic models) (62J12) Optimal statistical designs (62K05)

Abstract: We propose a new approach for identifying the support points of a locally optimal design when the model is a nonlinear model. In contrast to the commonly used geometric approach, we use an approach based on algebraic tools. Considerations are restricted to models with two parameters, and the general results are applied to often used special cases, including logistic, probit, double exponential and double reciprocal models for binary data, a loglinear Poisson regression model for count data, and the Michaelis--Menten model. The approach, which is also of value for multi-stage experiments, works both with constrained and unconstrained design regions and is relatively easy to implement.

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