A theoretical approach to the evolution and structural design of enzymatic networks; linear enzymatic chains, branched pathways and glycolysis of erythrocytes

MaRDI QIDQ1106136zbMATH OpenFDO

Authors Reinhart Heinrich, Hermann-Georg Holzhütter, Stefan Schuster

Publication date 1987

Published in Bulletin of Mathematical Biology (Search for Journal in Brave)

zbMATH Keywords

Lagrange multipliersnonlinearitiesbiochemistryMichaelis-Menten-type kineticsevolutionary pressureequilibrium concentrationsreaction ratesefficiency of enzymatic networksglycolysis of erythrocytesmetabolic efficiency

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Chemical kinetics in thermodynamics and heat transfer (80A30)

Recommendations

• Kinetic and thermodynamic constraints for the structural design of glycolysis
• scientific article; zbMATH DE number 880332
• Evolution of enzyme levels in metabolic pathways: a theoretical approach. I
• Minimization of intermediate concentrations as a suggested optimality principle for biochemical networks. II: Time hierarchy, enzymatic rate laws, and erythrocyte metabolism
• An evolutionary approach to enzyme kinetics: Optimization of ordered mechanisms

Cited in

(12)

• Evolutionary optimization of metabolic pathways. Theoretical reconstruction of the stoichiometry of ATP and NADH producing systems
• Optimizing enzymatic catalysts for rapid turnover of substrates with low enzyme sequestration
• Kinetic and thermodynamic principles determing the structural design of ATP-producing systems.
• Glycolytic oscillations and limits on robust efficiency
• Evolution of enzyme levels in metabolic pathways: a theoretical approach. II
• Minimization of intermediate concentrations as a suggested optimality principle for biochemical networks. I: Theoretical analysis
• Modelling, steady state analysis and optimization of the catalytic efficiency of the triosephosphate isomerase
• Effects of time delay on the dynamics of a kinetic model of a microbial fermentation process
• Is maximization of molar yield in metabolic networks favoured by evolution?
• An evolutionary approach to enzyme kinetics: Optimization of ordered mechanisms
• Kinetic and thermodynamic constraints for the structural design of glycolysis
• Evolution of enzyme levels in metabolic pathways: a theoretical approach. I

This page was built for publication: A theoretical approach to the evolution and structural design of enzymatic networks; linear enzymatic chains, branched pathways and glycolysis of erythrocytes

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q1106136)