The dynamics of infinitesimally rare alleles, applied to the evolution of mutation rates and the expression of deleterious mutations

DOI10.1006/TPBI.1998.1375zbMATH Open0967.92014OpenAlexW1981743818WikidataQ77928374 ScholiaQ77928374MaRDI QIDQ1284296FDOQ1284296

Authors: Kevin J. Dawson 

Publication date: 30 August 2001

Published in: Theoretical Population Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1006/tpbi.1998.1375

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zbMATH Keywords

deleterious mutationsfactorial cumulantsinfinitesimally rare alleles

Mathematics Subject Classification ID

Genetics and epigenetics (92D10) Problems related to evolution (92D15)

Cites Work

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• Modifiers of mutation rate: A general reduction principle
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• The accumulation of deleterious genes in a population - Muller's Ratchet
• Evolution of the mutation rate at a heterotic locus.
• Towards a theory of the evolution of modifier genes
• An evolutionary reduction principle for genetic modifiers.
• Mutation modification with multiplicative fertility selection
• Nonlinear analysis of some models for the evolution of dominance
• Dynamics of the classical genetic model for the evolution of dominance
• Linkage disequilibrium and the infinitesimal limit
• Clone-selection and optimal rates of mutation

Cited In (16)

• Change in frequency of a rare mutant allele: A general formula and applications to partial inbreeding models
• Recombination and the evolution of mutational robustness
• Mutation modification with multiplicative fertility selection
• A Mutation-Selection Model with Recombination for General Genotypes
• A generalized model of mutation-selection balance with applications to aging
• A stochastic model for the mutation-selection balance in an infinite asexual population with a genome of fixed size
• Competition at the mouse \(t\) complex: Rare alleles are inherently favored.
• Two linked loci under mutation-selection balance and Muller's ratchet
• The dynamical way to mutation-selection balance of an infinite population evolving on a truncated fitness landscape
• Cumulant dynamics of a population under multiplicative selection, mutation, and drift.
• Quasi-equilibrium theory for the distribution of rare alleles in a subdivided population: Justification and implications
• The structure of allelic diversity in the presence of purifying selection
• Life history and deleterious mutation rate coevolution
• Mutation landscapes
• Fixation of a deleterious allele under mutation pressure and finite selection intensity
• Selection, mutation and sexual reproduction in an infinite haploid population with a genome of finite length

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