The accumulation of deleterious genes in a population - Muller's Ratchet
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Publication:754110
DOI10.1016/0040-5809(78)90027-8zbMATH Open0415.92012OpenAlexW2080449796WikidataQ67444775 ScholiaQ67444775MaRDI QIDQ754110FDOQ754110
Authors: John Haigh 
Publication date: 1978
Published in: Theoretical Population Biology (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.1016/0040-5809(78)90027-8
Poisson distributionequilibrium stateWright-Fisher modelMuller's ratchetaccumulation of deleterious genesasexually reproducing population
Cites Work
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- Evolution in finite populations with infinitely many types
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Cited In (38)
- Fixation probability of a nonmutator in a large population of asexual mutators
- Muller's ratchet with compensatory mutations
- Quasi-equilibria and click times for a variant of Muller's ratchet
- The effect of recombination on the speed of evolution
- The effect of the reproductive system on mutation load
- Mutational meltdown in asexual populations doomed to extinction
- Limiting fitness distributions in evolutionary dynamics
- Fixation probabilities of additive alleles in diploid populations
- Generation of variation and a modified mean fitness principle: necessity is the mother of genetic invention
- Package models and the information crisis of prebiotic evolution
- A generalized model of mutation-selection balance with applications to aging
- A stochastic model for the mutation-selection balance in an infinite asexual population with a genome of fixed size
- Critical fitness collapse in three-dimensional spatial population genetics
- Absolute negative mobility in evolution
- The dynamics of infinitesimally rare alleles, applied to the evolution of mutation rates and the expression of deleterious mutations
- Role of epistasis on the fixation probability of a non-mutator in an adapted asexual population
- Within-host evolution and virulence in microparasites
- Competing islands limit the rate of adaptation in structured populations
- Muller's ratchet clicks in finite time
- Highly fit ancestors of a partly sexual haploid population
- Fluctuations in fitness distributions and the effects of weak linked selection on sequence evolution
- The spatial Muller's ratchet: surfing of deleterious mutations during range expansion
- Sexual recombination under the joint effects of mutation, selection, and random sampling drift
- Multi-site adaptation in the presence of infrequent recombination
- What is the difference between models of error thresholds and Muller's ratchet?
- Fifty years of theoretical population biology
- A stochastic model for a single click of Muller's ratchet
- The structure of allelic diversity in the presence of purifying selection
- Deterministic evolution of an asexual population under the action of beneficial and deleterious mutations on additive fitness landscapes
- Upper bound on the rate of adaptation in an asexual population
- Haigh (1978) and Muller's ratchet
- Effect of selection on the topology of genealogical trees
- Life history and deleterious mutation rate coevolution
- The traveling-wave approach to asexual evolution: Muller's ratchet and speed of adaptation
- Effect of drift, selection and recombination on the equilibrium frequency of deleterious mutations
- The optimum recombination rate that realizes the fastest evolution of a novel functional combination of many genes
- Asymptotic behavior of the rate of adaptation
- Diffusion approximations in population genetics and the rate of Muller's ratchet
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