Limiting fitness distributions in evolutionary dynamics

DOI10.1016/J.JTBI.2017.01.005zbMATH Open1368.92125arXiv1511.00296OpenAlexW2275726788WikidataQ38772667 ScholiaQ38772667MaRDI QIDQ2013427FDOQ2013427

Authors: Matteo Smerlak, Ahmed H. Youssef 

Publication date: 18 August 2017

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Abstract: Darwinian evolution can be modeled in general terms as a flow in the space of fitness (i.e. reproductive rate) distributions. In the diffusion approximation, Tsimring et al. have showed that this flow admits "fitness wave" solutions: Gaussian-shape fitness distributions moving towards higher fitness values at constant speed. Here we show more generally that evolving fitness distributions are attracted to a one-parameter family of distributions with a fixed parabolic relationship between skewness and kurtosis. Unlike fitness waves, this statistical pattern encompasses both positive and negative (a.k.a. purifying) selection and is not restricted to rapidly adapting populations. Moreover we find that the mean fitness of a population under the selection of pre-existing variation is a power-law function of time, as observed in microbiological evolution experiments but at variance with fitness wave theory. At the conceptual level, our results can be viewed as the resolution of the "dynamic insufficiency" of Fisher's fundamental theorem of natural selection. Our predictions are in good agreement with numerical simulations.

Full work available at URL: https://arxiv.org/abs/1511.00296

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zbMATH Keywords

evolutionary dynamicslimiting distributionFisher fundamental theorem of natural selection

Mathematics Subject Classification ID

Genetics and epigenetics (92D10) Problems related to evolution (92D15)

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Cited In (19)

• On the limit points of discrete selection dynamics
• Darwinian standard model of physics obtains general relativity
• Natural selection in compartmentalized environment with reshuffling
• Fisher's fundamental theorem of natural selection, dynamic sufficiency, and the necessity of higher moments
• Evolution of dietary diversity and a starvation driven cross-diffusion system as its singular limit
• Evolutionary Pareto distributions
• On the definition and measurement of fitness in finite populations
• Hypomixability Elimination In Evolutionary Systems
• Implications of long tails in the distribution of mutant effects
• Darwinian aspects of molecular evolution at sublinear propagation rates
• JSP special issue on statistical theory of biological evolution
• Natural selection as coarsening
• Thermodynamics and evolutionary biology through optimal control
• Finite populations induce metastability in evolutionary search.
• Upper bound on the rate of adaptation in an asexual population
• Large population limits for evolutionary dynamics with random matching
• Density-dependent selection and the limits of relative fitness
• Fitness potentials and qualitative properties of the Wright-Fisher dynamics
• Cryptic selection forces and dynamic heritability in generalized phenotypic evolution

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