The influence of fixed and free final time of treatment on optimal chemotherapeutic protocols

DOI10.1016/S0895-7177(98)00029-6zbMath0896.92015OpenAlexW1997551282MaRDI QIDQ1388959

M. I. S. Costa, José Luiz Boldrini

Publication date: 6 October 1998

Published in: Mathematical and Computer Modelling (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/s0895-7177(98)00029-6

zbMATH Keywords

free final timechemotherapeutic treatmentsexponential cell growthoptimal drug regimen

Mathematics Subject Classification ID

Differential games and control (49N70) Medical applications (general) (92C50) Pursuit and evasion games (49N75) Optimality conditions for problems involving ordinary differential equations (49K15)

Related Items (1)

The dynamics of an optimally controlled tumor model: A case study

Cites Work

• Role of optimal control theory in cancer chemotherapy
• Optimal control analysis in the chemotherapy of IgG multiple myeloma
• Singularity of optimal control in some problems related to optimal chemotherapy
• Drug kinetics and drug resistance in optimal chemotherapy
• Chemotherapeutic treatments involving drug resistance and level of normal cells as a criterion of toxicity
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