Drug kinetics and drug resistance in optimal chemotherapy
DOI10.1016/0025-5564(94)00027-WzbMATH Open0821.92015OpenAlexW2016908937WikidataQ52351078 ScholiaQ52351078MaRDI QIDQ1804871FDOQ1804871
J. L. Boldrini, M. I. S. Costa, Rodney C. Bassanezi
Publication date: 27 September 1995
Published in: Mathematical Biosciences (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.1016/0025-5564(94)00027-w
saturationtumor growthdrug resistancetoxicitydrug concentrationdrug decayfirst-order pharmacokinetics dynamicsmaximum allowed drug injectionoptimal chemotherapy
Medical applications (general) (92C50) Differential games and control (49N70) Pursuit and evasion games (49N75) Optimality conditions for problems involving ordinary differential equations (49K15) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)
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- Optimal control analysis in the chemotherapy of IgG multiple myeloma
- Role of optimal control theory in cancer chemotherapy
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Cited In (10)
- The influence of fixed and free final time of treatment on optimal chemotherapeutic protocols
- Chemotherapeutic treatments involving drug resistance and level of normal cells as a criterion of toxicity
- ANALYSIS OF A CELL-CYCLE SPECIFIC MODEL FOR CANCER CHEMOTHERAPY
- Optimization of the chemotherapy process on the base of the maximum principle
- Application of optimal control theory to analysis of cancer chemotherapy regimens
- A cellular automata model of chemotherapy effects on tumour growth: targeting cancer and immune cells
- Analysis of resonance chemotherapy in leukemia treatment via multi-staged population balance models
- Optimal multitherapy strategy in mathematical model of dynamics of the number of nonuniform tumor cells
- Chemotherapeutic treatments: A study of the interplay among drug resistance, toxicity and recuperation from side effects
- Conflicting objectives in chemotherapy with drug resistance
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