Replicability analysis for genome-wide association studies

DOI10.1214/13-aoas697zbMath1454.62340arXiv1209.2829OpenAlexW2042879443MaRDI QIDQ153020

Ruth Heller, Daniel Yekutieli, Daniel Yekutieli, Ruth Heller

Publication date: 1 March 2014

Published in: The Annals of Applied Statistics (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/1209.2829

zbMATH Keywords

empirical Bayesreplicationfalse discovery ratemeta-analysistype 2 diabetesreproducibilitycombined analysis

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Paired and multiple comparisons; multiple testing (62J15)

Related Items

False discovery rate control with unknown null distribution: is it possible to mimic the oracle?, Optimal detection of weak positive latent dependence between two sequences of multiple tests, Rejoinder on: ``Hierarchical inference for genome-wide association studies: a view on methodology with software, Distributed eQTL analysis with auxiliary information, Randomized ‐values for multiple testing and their application in replicability analysis, Testing partial conjunction hypotheses under dependency, with applications to meta-analysis, Replicability across multiple studies, Nonparametric false discovery rate control for identifying simultaneous signals, Replicability analysis for genome-wide association studies, repfdr, Admissibility in Partial Conjunction Testing, Covariate-Assisted Ranking and Screening for Large-Scale Two-Sample Inference, Semi-supervised multiple testing, Detecting multiple replicating signals using adaptive filtering procedures, Comments on: ``Hierarchical inference for genome-wide association studies: a view on methodology with software, Bayesian tests for composite alternative hypotheses in cross-tabulated data

Uses Software

• mixfdr
• fdrtool
• HAPGEN2

Cites Work

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