Improved inference of mutation rates. I: An integral representation for the Luria-Delbrück distribution

DOI10.1006/TPBI.2000.1496MaRDI QIDQ1597397zbMATH OpenOpenAlexWikidataFDO

Authors Thomas B. Kepler, Mihaela Oprea

Publication date 9 June 2003

Published in Theoretical Population Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1006/tpbi.2000.1496

zbMATH Keywords

integral representationmutation ratefinal cell numberinitial cell numberLuria-Delbrück distribution

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Problems related to evolution (92D15) Cell biology (92C37)

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Cites work

• scientific article; zbMATH DE number 3390587 (Why is no real title available?)
• SOLUTION OF A PROCESS OF RANDOM GENETIC DRIFT WITH A CONTINUOUS MODEL

Cited in

(23)

• Sampling HIV intrahost genealogies based on a model of acute stage CTL response
• A note on plating efficiency in fluctuation experiments
• Measuring bidirectional mutation
• On an unbiased and consistent estimator for mutation rates
• Analysis of the Luria–Delbrück distribution using discrete convolution powers
• Convergence results for compound Poisson distributions and applications to the standard Luria–Delbrück distribution
• Fluctuation analysis on mutation models with birth-date dependence
• Fast maximum likelihood estimation of mutation rates using a birth-death process
• A simple method for computing exact probabilities of mutation numbers
• An alternative derivation of the stationary distribution of the multivariate neutral Wright-Fisher model for low mutation rates with a view to mutation rate estimation from site frequency data
• Accumulation of neutral mutations in growing cell colonies with competition
• A new discrete distribution induced by the Luria-Delbrück mutation model
• The coalescence of intrahost HIV lineages under symmetric CTL attack
• Estimating change rates of genetic markers using serial samples: applications to the transposon IS6110 in Mycobacterium tuberculosis
• New approaches to mutation rate fold change in Luria-Delbrück fluctuation experiments
• An explicit representation of the Luria-Delbrück distribution
• Scaling solution in the large population limit of the general asymmetric stochastic Luria-Delbrück evolution process
• The fixed-size Luria-Delbrück model with a nonzero death rate
• Statistics for the Luria-Delbrück distribution
• Improved inference of mutation rates. II: Generalization of the Luria-Delbrück distribution for realistic cell-cycle time distributions
• Cellular replication limits in the Luria-Delbrück mutation model
• A generalized Luria-Delbrück model
• Mean field mutation dynamics and the continuous Luria-Delbrück distribution

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