A scheme for multiple sequence alignment optimization -- an improvement based on family representative mechanics features

DOI10.1016/j.jtbi.2009.08.028zbMath1403.92213OpenAlexW2108708392WikidataQ48258876 ScholiaQ48258876MaRDI QIDQ1628948

Xin Liu, Ya-Pu Zhao

Publication date: 11 December 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2009.08.028

zbMATH Keywords

multiple sequence alignmenthomologous proteinshydrophobic interactionscoring scheme

Mathematics Subject Classification ID

Protein sequences, DNA sequences (92D20)

Uses Software

• PSI-BLAST
• BLAST

Cites Work

• On the shortest spanning subtree of a graph and the traveling salesman problem
• Donut-shaped fingerprint in homologous polypeptide relationships -- a topological feature related to pathogenic structural changes in conformational disease
• Methods for assessing the statistical significance of molecular sequence features by using general scoring schemes.

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