Model prediction and validation of an order mechanism controlling the spatiotemporal phenotype of early hepatocellular carcinoma

DOI10.1007/S11538-017-0375-1MaRDI QIDQ1648977zbMATH OpenOpenAlexWikidataFDO

Authors Stefan Hoehme, Francois Bertaux, William Weens, Bettina Grasl-Kraupp, Jan G. Hengstler, Dirk Drasdo

Publication date 5 July 2018

Published in Bulletin of Mathematical Biology (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://doi.org/10.1007/s11538-017-0375-1

zbMATH Keywords

agent-based simulationcancer phenotypeliver cancermulticellular modelorder principle

Mathematics Subject Classification ID

Medical applications (general) (92C50) Cell biology (92C37)

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Cites work

• scientific article; zbMATH DE number 1528424 (Why is no real title available?)
• An overview of SuperLU
• Biomechanical and Nutrient Controls in the Growth of Mammalian Cell Populations
• COARSE GRAINING IN SIMULATED CELL POPULATIONS
• Individual-based models to growth and folding in one-layered tissues: intestinal crypts and early development.
• On the role of physics in the growth and pattern formation of multi-cellular systems: what can we learn from individual-cell based models?
• Patient-calibrated agent-based modelling of ductal carcinoma in situ (DCIS): from microscopic measurements to macroscopic predictions of clinical progression
• Single-cell-based models in biology and medicine.
• Vascular phenotype identification and anti-angiogenic treatment recommendation: a pseudo-multiscale mathematical model of angiogenesis

Cited in

(2)

• A model for hepatocarcinogenesis treating phenotypical changes in focal hepatocellular lesions as epigenetic events
• Mathematical oncology

Describes a project that uses

Uses Software

• CellSys
• TiQuant
• SuperLU

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