The geometry of partial fitness orders and an efficient method for detecting genetic interactions

DOI10.1007/S00285-018-1237-7zbMATH Open1398.92180OpenAlexW2953148552WikidataQ88599476 ScholiaQ88599476MaRDI QIDQ1784416FDOQ1784416

Authors: Caitlin Lienkaemper, Lisa Lamberti, James Drain, Niko Beerenwinkel, Alex Gavryushkin 

Publication date: 26 September 2018

Published in: Journal of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s00285-018-1237-7

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zbMATH Keywords

graph-theoretic approachgenetic interactionspartial fitness orders

Mathematics Subject Classification ID

Applications of graph theory (05C90) Genetics and epigenetics (92D10) Problems related to evolution (92D15)

Cites Work

• Geometry of the space of phylogenetic trees
• The space of ultrametric phylogenetic trees
• The combinatorics of discrete time-trees: theory and open problems
• Enumerative combinatorics. Volume 2.
• An $n^{5/2} $ Algorithm for Maximum Matchings in Bipartite Graphs
• Graph theory
• Epistasis and shapes of fitness landscapes
• Rational design of antibiotic treatment plans: a treatment strategy for managing evolution and reversing resistance

Cited In (4)

• Epistasis, regular subdivisions and spanning trees
• Structure of the \(\boldsymbol{G}\)-matrix in relation to phenotypic contributions to fitness
• An uncertainty law for microbial evolution
• Geometry of fitness landscapes: peaks, shapes and universal positive epistasis

Uses Software

• SageMath
• OEIS

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