The geometry of partial fitness orders and an efficient method for detecting genetic interactions

DOI10.1007/S00285-018-1237-7MaRDI QIDQ1784416zbMATH OpenOpenAlexWikidataFDO

Authors Caitlin Lienkaemper, Lisa Lamberti, James Drain, Niko Beerenwinkel, Alex Gavryushkin

Publication date 26 September 2018

Published in Journal of Mathematical Biology (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://doi.org/10.1007/s00285-018-1237-7

zbMATH Keywords

graph-theoretic approachgenetic interactionspartial fitness orders

Mathematics Subject Classification ID

Applications of graph theory (05C90) Genetics and epigenetics (92D10) Problems related to evolution (92D15)

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Cites work

• An $n^{5/2} $ Algorithm for Maximum Matchings in Bipartite Graphs
• Enumerative combinatorics. Volume 2.
• Epistasis and shapes of fitness landscapes
• Geometry of the space of phylogenetic trees
• Graph theory
• Rational design of antibiotic treatment plans: a treatment strategy for managing evolution and reversing resistance
• The combinatorics of discrete time-trees: theory and open problems
• The space of ultrametric phylogenetic trees

Cited in

(4)

• Epistasis, regular subdivisions and spanning trees
• Structure of the \(\boldsymbol{G}\)-matrix in relation to phenotypic contributions to fitness
• An uncertainty law for microbial evolution
• Geometry of fitness landscapes: peaks, shapes and universal positive epistasis

Describes a project that uses

Uses Software

• OEIS
• SageMath

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