Role of CaMKII and PKA in early afterdepolarization of human ventricular myocardium cell: a computational model study

DOI10.1155/2016/4576313zbMATH Open1368.92067DBLPjournals/cmmm/DaiZZXG16OpenAlexW2559792655WikidataQ37527310 ScholiaQ37527310MaRDI QIDQ2013943FDOQ2013943

Authors: Ling Dai, Yunliang Zang, Dingchang Zheng, Ling Xia, Yinglan Gong 

Publication date: 10 August 2017

Published in: Computational \& Mathematical Methods in Medicine (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1155/2016/4576313

Recommendations

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zbMATH Keywords

arrhythmogenesisCa\(^{2+}\)/calmodulin-dependent protein kinase IIearly afterdepolarization

Mathematics Subject Classification ID

Computational methods for problems pertaining to biology (92-08) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

Cited In (6)

• Electrophysiological effects of small conductance Ca\(^{2+}\)-activated K\(^+\) channels in atrial myocytes
• Dynamics of adrenergic signaling in cardiac myocytes and implications for pharmacological treatment
• Simulation of arrhythmogenic effect of rogue RyRs in failing heart by using a coupled model
• Big ducks in the heart: canard analysis can explain large early afterdepolarizations in cardiomyocytes
• Canards underlie both electrical and \(\mathrm{Ca}^{2+}\)-induced early afterdepolarizations in a model for cardiac myocytes
• In silico investigation into cellular mechanisms of cardiac alternans in myocardial ischemia

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