Selection, recombination, and the ancestral initiation graph

DOI10.1016/J.TPB.2021.08.001MaRDI QIDQ2076089zbMATH OpenOpenAlexFDO

Authors Frederic Alberti, C. Herrmann, Ellen Baake

Publication date 18 February 2022

Published in Theoretical Population Biology (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/2101.10080

zbMATH Keywords

population geneticslinkage disequilibriumhitchhikingselection-recombination differential equationancestral initiation graph

Mathematics Subject Classification ID

Problems related to evolution (92D15)

Abstract: Recently, the selection-recombination equation with a single selected site and an arbitrary number of neutral sites was solved by means of the ancestral selection-recombination graph. Here, we introduce a more accessible approach, namely the ancestral initiation graph. The construction is based on a discretisation of the selection-recombination equation. We apply our method to systematically explain a long-standing observation concerning the dynamics of linkage disequilibrium between two neutral loci hitchhiking along with a selected one. In particular, this clarifies the nontrivial dependence on the position of the selected site.

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Cited in

(10)

• scientific article; zbMATH DE number 1972808 (Why is no real title available?)
• Labeled partitions in action: recombination, selection, mutation and more
• Ancestral recombination graphs under non-random ascertainment, with applications to gene mapping
• More on selection for and against recombination
• Solving the selection-recombination equation: ancestral lines and dual processes
• Asymptotic sampling distributions made easy: loose linkage in the ancestral recombination graph
• Evolution with recombination as Gibbs sampling
• Single-crossover recombination and ancestral recombination trees
• The time to the ancestor along sequences with recombination
• On the Height and Length of the Ancestral Recombination Graph

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