Bounding the local average treatment effect in an instrumental variable analysis of engagement with a mobile intervention
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Publication:2135335
DOI10.1214/21-AOAS1476zbMATH Open1498.62255arXiv2008.06473OpenAlexW3049161394MaRDI QIDQ2135335FDOQ2135335
Authors: Andrew J. Spieker, Robert A. Greevy, L. A. Nelson, Lindsay S. Mayberry 
Publication date: 6 May 2022
Published in: The Annals of Applied Statistics (Search for Journal in Brave)
Abstract: Estimation of local average treatment effects in randomized trials typically requires an assumption known as the exclusion restriction in cases where we are unwilling to rule out unmeasured confounding. Under this assumption, any benefit from treatment would be mediated through the post-randomization variable being conditioned upon, and would be directly attributable to neither the randomization itself nor its latent descendants. Recently, there has been interest in mobile health interventions to provide healthcare support; such studies can feature one-way content and/or two-way content, the latter of which allowing subjects to engage with the intervention in a way that can be objectively measured on a subject-specific level (e.g., proportion of text messages receiving a response). It is hence highly likely that a benefit achieved by the intervention could be explained in part by receipt of the intervention content and in part by engaging with/responding to it. When seeking to characterize average causal effects conditional on post-randomization engagement, the exclusion restriction is therefore all but surely violated. In this paper, we propose a conceptually intuitive sensitivity analysis procedure for this setting that gives rise to sharp bounds on local average treatment effects. A wide array of simulation studies reveal this approach to have very good finite-sample behavior and to recover local average treatment effects under correct specification of the sensitivity parameter. We apply our methodology to a randomized trial evaluating a text message-delivered intervention for Type 2 diabetes self-care.
Full work available at URL: https://arxiv.org/abs/2008.06473
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Cites Work
- The Bias of Instrumental Variable Estimators
- Bootstrap methods for standard errors, confidence intervals, and other measures of statistical accuracy
- Principal stratification in causal inference
- Identification of Causal Effects Using Instrumental Variables
- Toward Causal Inference With Interference
- The central role of the propensity score in observational studies for causal effects
- Title not available (Why is that?)
- Identification and Estimation of Local Average Treatment Effects
- A new approach to causal inference in mortality studies with a sustained exposure period—application to control of the healthy worker survivor effect
- Two-Stage Least Squares Estimation of Average Causal Effects in Models with Variable Treatment Intensity
- Regression modeling strategies. With applications to linear models, logistic regression and survival analysis
- Assessing the Sensitivity of Regression Results to Unmeasured Confounders in Observational Studies
- Fully conditional specification in multivariate imputation
- Identification, inference and sensitivity analysis for causal mediation effects
- Randomization Inference With Imperfect Compliance in the ACE-Inhibitor After Anthracycline Randomized Trial
- Principal stratification with predictors of compliance for randomized trials with 2 active treatments
- Principal Stratification for Causal Inference With Extended Partial Compliance
- Clustered Encouragement Designs with Individual Noncompliance: Bayesian Inference with Randomization, and Application to Advance Directive Forms
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