A machine learning framework for predicting synergistic and antagonistic drug combinatorial efficacy

DOI10.1007/S10910-022-01331-0zbMATH Open1492.92027OpenAlexW4214508557MaRDI QIDQ2143447FDOQ2143447

Authors: Suyu Mei 

Publication date: 31 May 2022

Published in: Journal of Mathematical Chemistry (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s10910-022-01331-0

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zbMATH Keywords

machine learningdrug-drug interactionsignaling pathwaysdrug combination

Mathematics Subject Classification ID

Medical applications (general) (92C50) Biochemistry, molecular biology (92C40)

Cites Work

• LIBLINEAR: a library for large linear classification
• A simple generalisation of the area under the ROC curve for multiple class classification problems

Cited In (3)

• Machine learning in drug development: characterizing the effect of 30 drugs on the QT interval using Gaussian process regression, sensitivity analysis, and uncertainty quantification
• Multi-drug combination designs with experiments in silico
• A similarity-based method for prediction of drug side effects with heterogeneous information

Uses Software

• LIBLINEAR
• DrugBank

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