In silico synergism and antagonism of an anti-tumour system intervened by coupling immunotherapy and chemotherapy: a mathematical modelling approach

DOI10.1007/S11538-011-9693-XMaRDI QIDQ417370zbMATH OpenOpenAlexWikidataFDO

Authors Wenyong Hu, Wei-Rong Zhong, Feng-Hua Wang, Yuanzhi Shao, Li Li

Publication date 14 May 2012

Published in Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/s11538-011-9693-x

zbMATH Keywords

numerical simulationnonlinear dynamicspreclinical pharmacokinetics evaluationsynergism and antagonismtumour

Mathematics Subject Classification ID

Medical applications (general) (92C50) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

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Cites work

• scientific article; zbMATH DE number 2006091 (Why is no real title available?)
• Chemotherapy for tumors: An analysis of the dynamics and a study of quadratic and linear optimal controls
• Different strategies for cancer treatment: mathematical modelling
• Mathematical biology. Vol. 1: An introduction.
• Mixed immunotherapy and chemotherapy of tumors: feedback design and model updating schemes
• OPTIMAL CONTROL OF MIXED IMMUNOTHERAPY AND CHEMOTHERAPY OF TUMORS
• Optimal control for selected cancer chemotherapy ODE models: a view on the potential of optimal schedules and choice of objective function

Cited in

(3)

• Antagonism and negative side-effects in combination therapy for cancer
• Modelling the immune response to cancer: an individual-based approach accounting for the difference in movement between inactive and activated T cells
• A machine learning framework for predicting synergistic and antagonistic drug combinatorial efficacy

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