Modeling transport regulation in gene regulatory networks

DOI10.1007/S11538-022-01035-1MaRDI QIDQ2154545zbMATH OpenOpenAlexWikidataFDO

Authors Erika Fox, Bree Cummins, William Duncan, Tomáš Gedeon

Publication date 19 July 2022

Published in Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/s11538-022-01035-1

zbMATH Keywords

cellular transportgene regulatory networksoscillations

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Systems biology, networks (92C42)

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Cites work

• Analysis and generic properties of gene regulatory networks with graded response functions
• Chaos in neural and gene networks with hard switching
• Combinatorial representation of parameter space for switching networks
• Computing linear extensions for polynomial posets subject to algebraic constraints
• Dynamics of actively regulated gene networks
• Equilibria and their stability in networks with steep sigmoidal nonlinearities
• From structure to dynamics: frequency tuning in the p53-Mdm2 network. I: Logical approach
• From structure to dynamics: frequency tuning in the p53-Mdm2 network. II: Differential and stochastic approaches
• Global analysis of steady points for systems of differential equations with sigmoid interactions
• Global dynamics for steep nonlinearities in two dimensions
• Hidden dynamics. The mathematics of switches, decisions and other discontinuous behaviour
• scientific article; zbMATH DE number 41285 (Why is no real title available?)
• Introduction to focus issue: quantitative approaches to genetic networks
• Joint realizability of monotone Boolean functions
• Model rejection and parameter reduction via time series
• Qualitative simulation of genetic regulatory networks using piecewise-linear models
• Sensitive dependence on initial conditions in gene networks
• Stability and bifurcations of equilibria in networks with piecewise linear interactions

Cited in

(4)

• Biological transportation networks: Modeling and simulation
• Extending combinatorial regulatory network modeling to include activity control and decay modulation
• Quantifying robustness of the gap gene network
• A yeast cell cycle pulse generator model shows consistency with multiple oscillatory and checkpoint mutant datasets

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