A PDE model for protocell evolution and the origin of chromosomes via multilevel selection
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Publication:2168364
Abstract: The evolution of complex cellular life involved two major transitions: the encapsulation of self-replicating genetic entities into cellular units and the aggregation of individual genes into a collectively replicating genome. In this paper, we formulate a minimal model of the evolution of proto-chromosomes within protocells. We model a simple protocell composed of two types of genes: a "fast gene" with an advantage for gene-level self-replication and a "slow gene" that replicates more slowly at the gene level, but which confers an advantage for protocell-level reproduction. Protocell-level replication capacity depends on cellular composition of fast and slow genes. We use a partial differential equation to describe how the composition of genes within protocells evolves over time under within-cell and between-cell competition. We find that the gene-level advantage of fast replicators casts a long shadow on the multilevel dynamics of protocell evolution: no level of between-protocell competition can produce coexistence of the fast and slow replicators when the two genes are equally needed for protocell-level reproduction. By introducing a "dimer replicator" consisting of a linked pair of the slow and fast genes, we show analytically that coexistence between the two genes can be promoted in pairwise multilevel competition between fast and dimer replicators, and provide numerical evidence for coexistence in trimorphic competition between fast, slow, and dimer replicators. Our results suggest that dimerization, or the formation of a simple chromosome-like dimer replicator, can help to overcome the shadow of lower-level selection and work in concert with deterministic multilevel selection to allow for the coexistence of two genes that are complementary at the protocell-level but compete at the level of individual gene-level replication.
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Cites work
- A simple model of group selection that cannot be analyzed with inclusive fitness
- A unifying framework reveals key properties of multilevel selection
- Analysis of multilevel replicator dynamics for general two-strategy social dilemma
- Analytical results for individual and group selection of any intensity
- Coexistence and error propagation in pre-biotic vesicle models: a group selection approach
- Computer simulations of cellular group selection reveal mechanism for sustaining cooperation
- Deterministic Approximation of Stochastic Evolution in Games
- Diffusion models in population genetics
- Dynamic-persistence of cooperation in public good games when group size is dynamic
- Effect of migration in a diffusion model for template coexistence in protocells
- Elliptic partial differential equations of second order
- Evolution and equilibrium under inexact information.
- Evolution of cooperation under \(N\)-person snowdrift games
- Finite Volume Methods for Hyperbolic Problems
- Group-level events are catalysts in the evolution of cooperation
- scientific article; zbMATH DE number 3987100 (Why is no real title available?)
- scientific article; zbMATH DE number 3989157 (Why is no real title available?)
- Individual-based models under various time-scales
- Long-time behavior of a PDE replicator equation for multilevel selection in group-structured populations
- Maintenance of diversity in a hierarchical host-parasite model with balancing selection and reinfection
- Nonlinear group survival in Kimura's model for the evolution of altruism
- On the identification of the pointwise Hölder exponent of the generalized multifractional Brownian motion
- Scaling limits of a model for selection at two scales
- SOLUTION OF A PROCESS OF RANDOM GENETIC DRIFT WITH A CONTINUOUS MODEL
- Solutions of ordinary differential equations as limits of pure jump markov processes
- Some analytic results for Kimura diffusion operators
- Stationary solutions and their stability for Kimura's diffusion model with intergroup selection
- Stationary solutions and their stability for Kimura's diffusion model with intergroup selection. II
- Stochastic evolutionary dynamics on two levels
- Stochasticity, selection, and the evolution of cooperation in a two-level Moran model of the snowdrift game
- The replicator dynamics for multilevel selection in evolutionary games
- Wright-Fisher diffusion in one dimension
Cited in
(7)- Moderate sex between protocells can balance between a decrease in assortment load and an increase in parasite spread
- Selfishness versus functional cooperation in a stochastic protocell model
- A theoretical approach to the large-scale evolution of multicellularity and cell differentiation
- Assortment and reciprocity mechanisms for promotion of cooperation in a model of multilevel selection
- Mathematical modelling of molecule evolution in protocells
- Steady-state and dynamical behavior of a PDE model of multilevel selection with pairwise group-level competition
- Exploring the evolution of altruistic punishment with a PDE model of cultural multilevel selection
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