A spatial model of germinal center reactions: cellular adhesion based sorting of B cells results in efficient affinity maturation

DOI10.1016/S0022-5193(03)00010-9MaRDI QIDQ2177165zbMATH OpenOpenAlexWikidataFDO

Authors Can Keşmir, Rob J. De Boer

Publication date 6 May 2020

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/s0022-5193(03)00010-9

zbMATH Keywords

affinity maturationcellular adhesiongerminal center reactionsspatial model

Mathematics Subject Classification ID

Pathology, pathophysiology (92C32) Cell biology (92C37)

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Cites work

• Dynamics of one-pass germinal center models: implications for affinity maturation

Cited in

(7)

• Antigen-driven selection in germinal centers as reflected by the shape characteristics of immunoglobulin gene lineage trees: a large-scale simulation study
• The type of seeder cells determines the efficiency of germinal center reactions
• An analysis of B cell selection mechanisms in germinal centers
• A CONCERTED ACTION OF B CELL SELECTION MECHANISMS
• A model for migratory B cell oscillations from receptor down-regulation induced by external chemokine fields
• Germinal center dynamics during acute and chronic infection
• Dynamics of one-pass germinal center models: implications for affinity maturation

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