Sample size calculations for the differential expression analysis of RNA-seq data using a negative binomial regression model

DOI10.1515/sagmb-2018-0021zbMath1420.92087OpenAlexW2914372774WikidataQ91154025 ScholiaQ91154025MaRDI QIDQ2324965

Dongfeng Wu, Shesh N. Rai, Nigel G. F. Cooper, Xiao-Hong Li

Publication date: 12 September 2019

Published in: Statistical Applications in Genetics and Molecular Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1515/sagmb-2018-0021

zbMATH Keywords

sample sizeWald testRNA-seqpower analysisdifferentially expressed genes (DEGs)

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Protein sequences, DNA sequences (92D20)

Related Items (1)

Asymptotic inversion of the binomial and negative binomial cumulative distribution functions

Uses Software

• DEseq

Cites Work

• Unnamed Item
• Inferences and power analysis concerning two negative binomial distributions with an application to MRI lesion counts data
• The Use of Score Tests for Inference on Variance Components
• Small-sample estimation of negative binomial dispersion, with applications to SAGE data
• A Direct Approach to False Discovery Rates

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