A multiple timescale analysis of a mathematical model of the Wnt/\(\beta\)-catenin signalling pathway

DOI10.1007/s00285-009-0262-yzbMath1311.92094OpenAlexW2060200034WikidataQ33418420 ScholiaQ33418420MaRDI QIDQ2340034

Gary R. Mirams, Helen M. Byrne, John R. King

Publication date: 15 April 2015

Published in: Journal of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s00285-009-0262-y

zbMATH Keywords

asymptotic analysisODE modelWnt\(\beta\)-cateninAPC

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Cell biology (92C37)

Related Items (9)

Delay-driven oscillations via axin2 feedback in the Wnt/\(\beta\)-catenin signalling pathway ⋮ A theoretical investigation of the effect of proliferation and adhesion on monoclonal conversion in the colonic crypt ⋮ A kinetic model to study the regulation of \(\beta \)-catenin, APC, and axin in the human colonic crypt ⋮ Mathematical model for simulation of morphological changes associated to crypt fission in the colon ⋮ Reversible Doi and Smoluchowski Kinetics for High-Order Reactions ⋮ Multi-scale modeling of APC and \(\beta \)-catenin regulation in the human colonic crypt ⋮ Multiscale analysis of pattern formation via intercellular signalling ⋮ Chaste: A test-driven approach to software development for biological modelling ⋮ Nucleo-cytoplasmic shuttling of APC can maximize \(\beta\)-catenin/TCF concentration

Cites Work

• Perturbation methods in applied mathematics
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