Delay-driven oscillations via axin2 feedback in the Wnt/-catenin signalling pathway

DOI10.1016/J.JTBI.2020.110458MaRDI QIDQ827771zbMATH OpenOpenAlexWikidataFDO

Authors James C. Cavallo, Steffen Scholpp, Mark B. Flegg

Publication date 13 January 2021

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jtbi.2020.110458

zbMATH Keywords

applied dynamical systemdelayed-feedbacksystems biologyWnt-signalling

Mathematics Subject Classification ID

Systems biology, networks (92C42) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

Recommendations

• A multiple timescale analysis of a mathematical model of the Wnt/\(\beta\)-catenin signalling pathway
• Elucidating the interactions between the adhesive and transcriptional functions of \(\beta\)-catenin in normal and cancerous cells
• A kinetic model to study the regulation of \(\beta \)-catenin, APC, and axin in the human colonic crypt
• The segmentation clock in mice: interaction between the Wnt and Notch signalling pathways
• Modeling the segmentation clock as a network of coupled oscillations in the notch, Wnt and FGF signaling pathways

Cites work

• A multiple timescale analysis of a mathematical model of the Wnt/\(\beta\)-catenin signalling pathway
• Combining Intra- and Inter-cellular Dynamics to Investigate Intestinal Homeostasis

Cited in

(9)

• Switch-like behavior enables Wnt11 concentration specific response during dorso-ventral axis formation in \textit{Xenopus laevis}
• Nucleo-cytoplasmic shuttling of APC can maximize -catenin/TCF concentration
• Fixed and distributed gene expression time delays in reaction-diffusion systems
• Elucidating the interactions between the adhesive and transcriptional functions of \(\beta\)-catenin in normal and cancerous cells
• A multiple timescale analysis of a mathematical model of the Wnt/\(\beta\)-catenin signalling pathway
• A kinetic model to study the regulation of \(\beta \)-catenin, APC, and axin in the human colonic crypt
• A mathematical modelling portrait of Wnt signalling in early vertebrate embryogenesis
• scientific article; zbMATH DE number 7706658 (Why is no real title available?)
• Turing pattern formation in reaction-cross-diffusion systems with a bilayer geometry

This page was built for publication: Delay-driven oscillations via axin2 feedback in the Wnt/\(\beta\)-catenin signalling pathway

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q827771)