Quasi-steady state in the Michaelis-Menten system

DOI10.1016/j.nonrwa.2006.08.004zbMath1128.92014OpenAlexW2066530583MaRDI QIDQ2470131

Lena Noethen, Sebastian Walcher

Publication date: 13 February 2008

Published in: Nonlinear Analysis. Real World Applications (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.nonrwa.2006.08.004

zbMATH Keywords

invariant setdifferential inequalitymonotone systemenzyme-catalyzed reaction

Mathematics Subject Classification ID

Dynamical systems in biology (37N25) Initial value problems, existence, uniqueness, continuous dependence and continuation of solutions to ordinary differential equations (34A12) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Qualitative investigation and simulation of ordinary differential equation models (34C60) Differential inequalities involving functions of a single real variable (34A40)

Related Items

New trends and perspectives in nonlinear intracellular dynamics: one century from Michaelis-Menten paper ⋮ Evolutionary Γ-convergence of gradient systems modeling slow and fast chemical reactions ⋮ Quasi steady state and partial equilibrium approximations: their relation and their validity ⋮ On the anti-quasi-steady-state conditions of enzyme kinetics ⋮ Extension and justification of quasi-steady-state approximation for reversible bimolecular binding ⋮ Natural parameter conditions for singular perturbations of chemical and biochemical reaction networks ⋮ Algorithmic criteria for the validity of quasi-steady state and partial equilibrium models: the Michaelis-Menten reaction mechanism ⋮ Is there anything left to say on enzyme kinetic constants and quasi-steady state approximation? ⋮ Computing quasi-steady state reductions ⋮ A reconstruction of object properties with significant uncertainties ⋮ Reduced models of networks of coupled enzymatic reactions

Cites Work

• Unnamed Item
• Unnamed Item
• Unnamed Item
• Unnamed Item
• Michaelis-Menten kinetics at high enzyme concentrations
• Asymptotic analysis. Reprint
• Effects of periodic input on the quasi-steady state assumptions for enzyme-catalysed reactions
• Enzyme kinetics at high enzyme concentration
• On the validity of the steady state assumption of enzyme kinetics
• Phase-plane analyses of the Michaelis-Menten reaction equations
• Asymptotic analysis of the Michaelis-Menten reaction equations
• Geometric singular perturbation theory for ordinary differential equations
• Mathematical biology. Vol. 1: An introduction.
• Ordinary differential equations. An introduction to nonlinear analysis. Transl. from the German by Gerhard Metzen
• Quasi-steady state assumptions for non-isolated enzyme-catalysed reactions
• Extending the quasi-steady state approximation by changing variables
• Approximate invariance and differential inclusions in Hilbert spaces
• Monotonicity properties of the Michaelis-Menten reactions of enzyme kinetics
• Systems of Differential Equations Which Are Competitive or Cooperative: I. Limit Sets
• The Quasi-Steady-State Assumption: A Case Study in Perturbation