New trends and perspectives in nonlinear intracellular dynamics: one century from Michaelis-Menten paper

DOI10.1007/s00161-014-0367-4zbMath1341.92020OpenAlexW1998842497MaRDI QIDQ2629039

Guido Dell'Acqua, Enrico Bersani, Morten Gram Pedersen, Alberto Maria Bersani

Publication date: 19 July 2016

Published in: Continuum Mechanics and Thermodynamics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s00161-014-0367-4

zbMATH Keywords

singular perturbationsasymptotic expansionsMichaelis-Menten kineticsquasi-steady-state approximations

Mathematics Subject Classification ID

History of mathematics in the 20th century (01A60) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Biochemistry, molecular biology (92C40) History of biology (92-03)

Related Items (20)

Tihonov theory and center manifolds for inhibitory mechanisms in enzyme kinetics ⋮ Evolution of bone tissue based on angiogenesis as a crucial factor: New mathematical attempt ⋮ Approximation of enzyme kinetics for high enzyme concentration by a first order perturbation approach ⋮ An alternative approach to Michaelis-Menten kinetics that is based on the renormalization group ⋮ Heineken, Tsuchiya and Aris: ``On the mathematical status of the pseudo-steady state hypothesis. A classic from Volume 1 of \textit{Mathematical Biosciences} ⋮ Approaches for the estimation of timescales in nonlinear dynamical systems: timescale separation in enzyme kinetics as a case study ⋮ In-depth gaze at the astonishing mechanical behavior of bone: A review for designing bio-inspired hierarchical metamaterials ⋮ Algorithmic criteria for the validity of quasi-steady state and partial equilibrium models: the Michaelis-Menten reaction mechanism ⋮ Uniform Asymptotic Expansions beyond the tQSSA for the Goldbeter--Koshland Switch ⋮ The quasi-steady-state approximations revisited: timescales, small parameters, singularities, and normal forms in enzyme kinetics ⋮ Michaelis-Menten equation for degradation of insoluble substrate ⋮ Metabolic rate constants: some computational aspects ⋮ Long-term behaviours of autocatalytic sets ⋮ On a stochastic approach to model the double phosphorylation/dephosphorylation cycle ⋮ A study case for the analysis of asymptotic expansions beyond the tQSSA for inhibitory mechanisms in enzyme kinetics. ⋮ Characteristic, completion or matching timescales? An analysis of temporary boundaries in enzyme kinetics ⋮ General mathematical formula for near equilibrium relaxation kinetics of basic enzyme reactions and its applications to find conformational selection steps ⋮ A new Michaelis-Menten equation valid everywhere multi-scale dynamics prevails ⋮ Singular Perturbation Techniques and Asymptotic Expansions for Some Complex Enzyme Reactions ⋮ Hunting $\varepsilon$: The Origin and Validity of Quasi-Steady-State Reductions in Enzyme Kinetics

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