Algorithmic asymptotic analysis of the NF- B signaling system

DOI10.1016/J.CAMWA.2012.11.004MaRDI QIDQ2629460zbMATH OpenOpenAlexFDO

Authors Panayotis D. Kourdis, Athanasia G. Palasantza, Dimitrios A. Goussis

Publication date 6 July 2016

Published in Computers & Mathematics with Applications (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.camwa.2012.11.004

zbMATH Keywords

asymptotic analysiscomputational singular perturbationNF-\(\kappa\mathrm B\) signaling system

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Systems biology, networks (92C42)

Recommendations

• A method of `speed coefficients' for biochemical model reduction applied to the NF-\(\kappa\)B system
• A simple model of NF-\(\kappa\)B dynamics reproduces experimental observations
• Mathematical model of NF-\( \kappa\)B regulatory module
• A systematic survey of the response of a model NF-\(\kappa\)B signalling pathway to \(\mathrm{TNF}\alpha\) stimulation
• On the effect of circadian oscillations on biochemical cell signaling by NF- B

Cites work

• An efficient iterative algorithm for the approximation of the fast and slow dynamics of stiff systems
• Analysis of methane-air edge flame structure
• Asymptotic Solution of Stiff PDEs with the CSP Method: The Reaction Diffusion Equation
• Explicit time-scale splitting algorithm for stiff problems: Auto-ignition of gaseous mixtures behind a steady shock
• Fast and Slow Dynamics for the Computational Singular Perturbation Method
• Higher order corrections in the approximation of low-dimensional manifolds and the construction of simplified problems with the CSP method
• Mathematical model of NF-\( \kappa\)B regulatory module
• Model Reduction and Physical Understanding of Slowly Oscillating Processes: The Circadian Cycle
• Physical understanding of complex multiscale biochemical models via algorithmic simplification: glycolysis in saccharomyces cerevisiae
• Quasi steady state and partial equilibrium approximations: their relation and their validity
• Robust stability and instability of biochemical networks with parametric uncertainty
• Two perspectives on reduction of ordinary differential equations

Cited in

(14)

• A new Michaelis-Menten equation valid everywhere multi-scale dynamics prevails
• The ``hidden dynamics of the Rössler attractor
• Methods of model reduction for large-scale biological systems: a survey of current methods and trends
• A method of `speed coefficients' for biochemical model reduction applied to the NF-\(\kappa\)B system
• Editorial: Grasping complexity
• Glycolysis in saccharomyces cerevisiae: algorithmic exploration of robustness and origin of oscillations
• Asymptotic analysis of a target-mediated drug disposition model: algorithmic and traditional approaches
• Geometry of the Computational Singular Perturbation Method
• Mathematics of the NFAT Signaling Pathway
• NH₃ vs. CH₄ autoignition: A comparison of chemical dynamics
• H₂/air autoignition: The nature and interaction of the developing explosive modes
• Algorithmic criteria for the validity of quasi-steady state and partial equilibrium models: the Michaelis-Menten reaction mechanism
• Asymptotic analysis of a TMDD model: when a reaction contributes to the destruction of its product
• Format-preserving reduction of canonical nonlinear models

This page was built for publication: Algorithmic asymptotic analysis of the NF-\(\kappa\mathrm B\) signaling system

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q2629460)