Asymptotic stability of the stationary solution for a parabolic-hyperbolic free boundary problem modeling tumor growth

DOI10.1137/130906271MaRDI QIDQ2870593zbMATH OpenOpenAlexFDO

Authors Shangbin Cui

Publication date 21 January 2014

Published in SIAM Journal on Mathematical Analysis (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/1303.3667

zbMATH Keywords

nonlinear parabolic equationnonlinear hyperbolic equationfree boundary problem, asymptotic behaviorspherically symmetric unknown functionsthree-dimensional free boundary problem

Mathematics Subject Classification ID

Stability in context of PDEs (35B35) Asymptotic behavior of solutions to PDEs (35B40) Singular perturbations in context of PDEs (35B25) Semilinear parabolic equations (35K58) Free boundary problems for PDEs (35R35) First-order hyperbolic equations (35L02)

Abstract: This paper studies asymptotic behavior of solutions of a free boundary problem modeling the growth of tumors with two species of cells: proliferating cells and quiecent cells. In previous literatures it has been proved that this problem has a unique stationary solution which is asymptotically stable in the limit case $varepsilon=0$. In this paper we consider the more realistic case $0<varepsilon<<1$. In this case, after suitable reduction the model takes the form of a coupled system of a parabolic equation and a hyperbolic system, so that it is more difficult than the limit case $varepsilon=0$. By using some unknown variable transform as well as the similarity transform technique developed in our previous work, we prove that the stationary solution is also asymptotically stable in the case $0<varepsilon<<1$.

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