Asymptotic stability of stationary solutions of a free boundary problem modeling the growth of tumors with fluid tissues

DOI10.1137/080726550MaRDI QIDQ5190239zbMATH OpenOpenAlexFDO

Authors Junde Wu, Shangbin Cui

Publication date 15 March 2010

Published in SIAM Journal on Mathematical Analysis (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/0806.1363

zbMATH Keywords

Stokes equationsthreshold valueradial stationary solution

Mathematics Subject Classification ID

Stability in context of PDEs (35B35) Asymptotic behavior of solutions to PDEs (35B40) Free boundary problems for PDEs (35R35) Other free boundary flows; Hele-Shaw flows (76D27)

Abstract: This paper aims at proving asymptotic stability of the radial stationary solution of a free boundary problem modeling the growth of nonnecrotic tumors with fluid-like tissues. In a previous paper we considered the case where the nutrient concentration $sigma$ satisfies the stationary diffusion equation $Deltasigma=f(sigma)$, and proved that there exists a threshold value $gamm{a}_{\ast }>0$ for the surface tension coefficient $gamma$, such that the radial stationary solution is asymptotically stable in case $gamma>gamm{a}_{\ast }$, while unstable in case $gamma<gamm{a}_{\ast }$. In this paper we extend this result to the case where $sigma$ satisfies the non-stationary diffusion equation $epslnpartia{l}_{t}sigma=Deltasigma-f(sigma)$. We prove that for the same threshold value $gamm{a}_{\ast }$ as above, for every $gamma>gamm{a}_{\ast }$ there is a corresponding constant $epsl{n}_0(gamma)>0$ such that for any $0<epsln<epsl{n}_0(gamma)$ the radial stationary solution is asymptotically stable with respect to small enough non-radial perturbations, while for $0<gamma<gamm{a}_{\ast }$ and $epsln$ sufficiently small it is unstable under non-radial perturbations.

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• Global existence and asymptotic stability for an elliptic-parabolic free boundary problem: An application to a model of tumor growth
• Analysis of a mathematical model for tumor growth with Gibbs-Thomson relation
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